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RIBOSOMAL PROTEIN S6 KINASES, 90-KDA
Descriptors Found:
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DeCS
Descriptor
English
:
Ribosomal Protein S6 Kinases, 90-kDa
Descriptor
Spanish
:
Proteínas Quinasas S6 Ribosómicas 90-kDa
Descriptor
Portuguese
:
Proteínas Quinases S6 Ribossômicas 90-kDa
Synonyms
English
:
MAP-Kinase-Activated Kinase 1
MAP-Kinase-Activated Protein Kinase 1
Tree Number:
D08.811.913.696.620.682.700.862.500
D12.644.360.600.500
D12.776.476.600.500
Definition
English
:
A
family
of
ribosomal protein S6 kinases
that are structurally distinguished from
RIBOSOMAL PROTEIN S6 KINASES
, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered
RIBOSOMAL PROTEIN S6 KINASES
, members of this
family
are activated via the
MAP KINASE SIGNALING SYSTEM
and have been shown to act on a diverse array of
substrates
that are involved in cellular regulation such as
RIBOSOMAL PROTEIN S6
and CAMP RESPONSE ELEMENT-BINDING PROTEIN.
History Note
English
:
2005(2002); for PP90(RSK) & PP90(RSK) use RIBOSOMAL PROTEIN S6 KINASES 1998-2002
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
37342
Unique Identifier:
D038744
Occurrence in VHL
:
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