Search on: RIBOSOMAL PROTEIN S6 KINASES, 90-KDA 
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Descriptor English:   Ribosomal Protein S6 Kinases, 90-kDa 
Descriptor Spanish:   Proteínas Quinasas S6 Ribosómicas 90-kDa 
Descriptor Portuguese:   Proteínas Quinases S6 Ribossômicas 90-kDa 
Synonyms English:   MAP-Kinase-Activated Kinase 1
MAP-Kinase-Activated Protein Kinase 1  
Tree Number:   D08.811.913.696.620.682.700.862.500
D12.644.360.600.500
D12.776.476.600.500
Definition English:   A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN. 
History Note English:   2005(2002); for PP90(RSK) & PP90(RSK) use RIBOSOMAL PROTEIN S6 KINASES 1998-2002 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   37342 
Unique Identifier:   D038744 

Occurrence in VHL:
 

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